The crash closed the left lane of the westbound highway for several hours in Warren County, police said.
A single-vehicle crash Friday morning on Interstate 80 in Warren County resulted in serious injuries to the driver, according to New Jersey State Police.
It was reported about 10:10 a.m. on I-80 West at mile-marker 12 in Hope Township.
The vehicle left the highway to the left, entered the grassy median and came to rest in a ditch, Trooper Lawrence Peele said.
The driver was taken by ambulance to Hackettstown Medical Center and was in serious condition Friday afternoon, Peele said. A passenger was uninjured.
Police were continuing to investigate what caused the driver to lose control, and authorities were not immediately releasing the names of those involved.
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The left lane of the highway was closed in the area until about 1 p.m., according to the New Jersey Department of Transportation.
Kurt Bresswein may be reached at kbresswein@lehighvalleylive.com. Follow him on Twitter @KurtBresswein. Find lehighvalleylive.com on Facebook.